Co-infection of urogenital schistosomiasis and malaria and its association with anaemia and malnutrition amongst schoolchildren in Dutse, Nigeria

Hafizu Muhammed; Joshua B. Balogun; Musa M.  Dogara; Babatunde Adewale; Abdulganiyu A. Ibrahim; Chinedu B. Okolugbo; Graham Jackson

doi:10.17159/sajs.2023/13846

Authors

Hafizu Muhammed Department of Biological Sciences, Federal University, Dutse, Nigeria https://orcid.org/0000-0002-2060-3218
Joshua B. Balogun Department of Biological Sciences, Federal University, Dutse, Nigeria https://orcid.org/0000-0001-5644-8582
Musa M. Dogara Department of Biological Sciences, Federal University, Dutse, Nigeria https://orcid.org/0000-0003-3362-0452
Babatunde Adewale Public Health and Epidemiology Department, Nigeria Institute for Medical Research, Lagos, Nigeria https://orcid.org/0000-0002-9811-0333
Abdulganiyu A. Ibrahim Department of Nutrition and Dietetics, Jigawa State Polytechnic, Dutse, Nigeria https://orcid.org/0000-0002-0654-4928
Chinedu B. Okolugbo Department of Animal and Environmental Biology, Delta State University, Abraka, Nigeria https://orcid.org/0000-0003-2755-2027
Graham Jackson Department of Chemistry, University of Cape Town, Cape Town, South Africa https://orcid.org/0000-0002-4243-5470

DOI:

https://doi.org/10.17159/sajs.2023/13846

Keywords:

urogenital schistosomiasis, malaria, anaemia, malnutrition, co-infection

Abstract

Schistosomiasis is a neglected tropical disease. Sub-Saharan Africa accounts for 93% of the world’s 207 million schistosomiasis cases. Urogenital schistosomiasis and malaria are both public health problems in Nigeria, where they are endemic. We determined the co-prevalence of urogenital schistosomiasis and malaria in schoolchildren and assessed its implication on anaemia and malnutrition. This cross-sectional study was conducted amongst primary schoolchildren in the Warwade, Saya Saya and Jigawar Daha villages of Nigeria. Urine samples were collected to detect Schistosoma haematobium eggs, and finger prick blood was used for haemoglobin concentration and malaria diagnosis. Nutritional status was assessed using anthropometric measurements and a pre-tested questionnaire. The overall prevalence and density of S. haematobium were 27.7% and 9 eggs/10 mL, respectively, with significant differences between villages and sexes. The prevalence of malaria and infection density was 10.4% and 330 mps/μL, respectively. Co-infection prevalence was 3.3%. Anaemia prevalence was 66%, with significant variation across villages and between sexes. Prevalence of stunting, underweight, and wasting was 41.7%, 46%, and 29.7%, respectively. Mean haemoglobin concentrations in Plasmodium and children co-infected with urogenital schistosomiasis were significantly lower than those who were negative for the infection. No significant association was observed between malnutrition and single or co-infection of urogenital schistosomiasis and malaria. After adjusting for variables associated with anaemia, village of residence remained a significant predictor of anaemia. Water contact activities, such as fishing, swimming, and irrigation, emerged as independent risk factors of S. haematobium infection.

Significance:

Urogenital schistosomiasis and malaria infections are prevalent in communities around Warwade dam in Dutse, Nigeria, and cause anaemia. Continuous monitoring, proper treatment and regular intervention is desirable in the communities.